Decreased locomotor activity in mice expressing tTA under control of the CaMKIIα promoter
نویسندگان
چکیده
B. C. McKinney, J. S. Schneider, G. L. Schafer, J. L. Lowing, S. Mohan, M. X. Zhao, M. Y. Heng, R. L. Albin**, A. F. Seasholtz, H. Akil and G. G. Murphy* Medical Scientist Training Program, Neuroscience Program, Molecular & Behavioral Neuroscience Institute, Department of Neurology, **Ann Arbor Veterans Administration Medical Center GRECC, Department of Biological Chemistry, and Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA *Corresponding author: G. G. Murphy, PhD, University of Michigan, Molecular and Behavioral Neuroscience Institute, 5037 Biomedical Sciences Research Building, 109 Zina Pitcher Place, Ann Arbor, MI 48109-2200, USA. E-mail: [email protected]
منابع مشابه
Optogenetic Activation of the Excitatory Neurons Expressing CaMKIIα in the Ventral Tegmental Area Upregulates the Locomotor Activity of Free Behaving Rats
The ventral tegmental area (VTA) plays an important role in motivation and motor activity of mammals. Previous studies have reported that electrical stimulations of the VTA's neuronal projections were able to upregulate the locomotor activity of behaving rats. However, which types of neurons in the VTA that take part in the activation remain elusive. In this paper we employed optogenetic techni...
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